Overview

　　The Guanshentai 96-well deep-well plate automatic filling and sealing machine is an integrated system designed specifically for the micro-volume liquid filling and heat-sealing of 96/384-well deep-well plates, microplates, and PCR plates. The equipment combines automatic plate feeding, multi-channel micro-volume quantitative filling, heat-seal film feeding, heat-sealing, seal inspection, and finished product discharge into a single unit. The entire line automates the process from empty plates to filled and sealed finished plates, capable of processing 80–120 standard deep-well plates per hour; it serves as core automation equipment for high-throughput sample processing in the biopharmaceutical and in vitro diagnostic (IVD) sectors.

　　Key Advantages:

　　High-Precision Micro-Volume Filling: Utilizes a high-precision ceramic piston pump or peristaltic pump metering system to perform parallel filling across the entire 96-well plate. It supports dispensing volumes ranging from 10 μL to 2 mL per well with filling accuracy stable within ±1.0%, effectively eliminating cross-contamination between wells and volume inconsistencies.

　　Anti-Drip Filling Nozzles: Equipped with an independent nozzle lifting mechanism and a suck-back anti-drip system. Nozzles automatically retract after filling to prevent residual droplets, ensuring no liquid remains on well walls or the plate surface—making it ideal for the precise dispensing of expensive reagents and micro-volume samples.

　　Precision Heat-Sealing System: Employs constant-temperature heat-sealing technology with independently adjustable temperature, pressure, and time settings. The seal is smooth, secure, and free of wrinkles or bubbles, ensuring a complete, leak-proof seal that effectively prevents sample evaporation and cross-contamination. It supports various roll-film materials, including breathable films and aluminum foil films.

　　In-Line Seal Quality Inspection: Integrates a seal quality inspection module (based on mechanical/physical detection principles rather than AI self-learning). It inspects seal integrity plate-by-plate using pressure decay or visual comparison methods, automatically identifying and rejecting defects such as incomplete seals, torn films, or misalignment to ensure a high seal pass rate.

　　Clean-room Compatible Design: The unit features an SUS304 stainless steel frame and transparent protective covers. The filling and sealing zones meet GMP Class 100 cleanroom standards; the machine can operate inside biosafety cabinets or cleanrooms and supports UV sterilization environments.

　　Multi-format Compatibility: By swapping plate tracks and filling nozzle assemblies, the system accommodates standard SBS-format 96-well and 384-well deep-well plates, as well as various PCR and ELISA plates. It meets diverse filling and sealing requirements and allows for flexible, convenient product changeovers.

　　No-Plate, No-Fill/Seal Protection: Equipped with photoelectric sensors and plate-detection mechanisms, the system prevents filling or sealing when no plate is present, thereby avoiding material waste and unnecessary equipment idling.

　　User-Friendly Operation: Controlled via PLC and a touchscreen HMI, parameters such as dispense volume, flow rate, and heat-sealing temperature, pressure, and time can be set with a single touch; multiple recipes can be saved. It supports barcode scanning for batch data entry, facilitating data traceability and management.

　　Applications:

　　Widely applicable to micro-volume liquid filling and heat-sealing for 96/384-well deep-well plates in fields such as biopharmaceuticals (vaccine adjuvant dispensing, antibody diluent filling, enzyme preparation dispensing), in vitro diagnostics (IVD) (PCR master mix dispensing, nucleic acid extraction kit filling, diagnostic reagent dispensing), food testing (veterinary drug residue sample prep, microbial enrichment broth dispensing), and scientific research (compound library preparation, cell culture media dispensing, sample repository construction). With its exceptional precision, efficiency, and cleanliness, the Guanshentai 96-well deep-well plate automatic filling and sealing machine helps life science and IVD manufacturers upgrade to standardized, scalable production for microplate filling and sealing processes.

　　Equipment Details:

　　Model Number: GST-SWYP004A

　　Sizes: L4200*W1200*H1800 (mm)

　　Production Capacities: 600-700 boxes/hour

　　Filling volume:50-800uL

　　Total power:5KW

　　Power supply voltage:220V/50HZ

　　Weight:1200KG

　　Customized Support: Yes